Book Chapter
Cytokine-Induced Acute Inflammatory Monoarticular Arthritis
Adrian Achuthan, Ming-Chin Lee, Reem Saleh, Andrew J Fleetwood, John A Hamilton, Andrew D Cook
MACROPHAGES: METHODS AND PROTOCOLS | Methods in Molecular Biology | HUMANA PRESS INC | Published : 2018
Abstract
Animal models of arthritis enable us to investigate the pathogenesis of the disease and also to evaluate new therapies. Here we describe two different acute inflammatory monoarticular arthritis models (mBSA/IL1β and mBSA/GM-CSF) providing a more rapid and potentially simplified approach to investigate the pathogenesis.