Journal article
Assessment and management of bone health in women with oestrogen receptor-positive breast cancer receiving endocrine therapy: Position statement of the Endocrine Society of Australia, the Australian and New Zealand Bone & Mineral Society, the Australasian Menopause Society and the Clinical Oncology Society of Australia
M Grossmann, SK Ramchand, F Milat, A Vincent, E Lim, MA Kotowicz, J Hicks, H Teede
Clinical Endocrinology | WILEY | Published : 2018
DOI: 10.1111/cen.13735
Abstract
To formulate clinical consensus recommendations on bone health assessment and management of women with oestrogen receptor-positive early breast cancer receiving endocrine therapy, representatives appointed by relevant Australian Medical Societies used a systematic approach for adaptation of guidelines (ADAPTE) to derive an evidence-informed position statement addressing 5 key questions. Women receiving adjuvant aromatase inhibitors and the subset of premenopausal woman treated with tamoxifen have accelerated bone loss and increased fracture risk. Both bisphosphonates and denosumab prevent bone loss; additionally, denosumab has proven antifracture benefit. Women considering endocrine therapy ..
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Funding Acknowledgements
The authors would like to thank the ESA Council (chair Associate Professor Warrick Inder), the ANZBMS Council (chair Professor Emma Duncan during the writing and reviewing of this report), the ANZBMS Therapeutics Committee (chair Professor Richard Prince), the ANZBMS Densitometry Committee (chair Associate Professor Nicholas Pocock), the AMS board members, the AMS Executive Director and AMS Past Presidents Doctors Jane Elliott and Anna Fenton, and the COSA council (chair Professor Phyllis Butow) for their support, expert reviews and valuable contributions to this manuscript.