Journal article

Shining a Light on Alport Syndrome

Lorna J Hale, Melissa H Little

Cell Chemical Biology | CELL PRESS | Published : 2018

Abstract

In this issue of Cell Chemical Biology, Omachi et al. (2018) present a split Nanoluciferase system to identify successful protein trimerization in Alport syndrome. This elegant proof of concept suggests opportunities for drug screening for Alport syndrome and may be transferable to the study of other diseases affecting protein-protein interactions.