Regulatory genes controlling the synthesis of heavy chains of human immunoglobulin-G.

Abstract

The production of immunoglobulins is controlled by a combination of genes. It appears that most individuals carry genes for both types of immunoglobulin, Gm(a) and Gm(b). Whether or not these genes actually find expression in the phenotype, however, seems to depend on the action of regulatory genes which can control the expression of the cistrons coding for Gm(a) or Gm(b). © 1967 Nature Publishing Group.