Nano-assemblies of cationic mPEG brush block copolymers with gadolinium polyoxotungstate [Gd(W5O18)(2)](9-) form stable, high relaxivity MRI contrast agents
Joanne Ly, Yuhuan Li, Mai N Vu, Bradford A Moffat, Kevin S Jack, John F Quinn, Michael R Whittaker, Thomas P Davis
Nanoscale | ROYAL SOC CHEMISTRY | Published : 2018
Awarded by Australian Research Council (ARC) Centre of Excellence in Convergent Bio-Nano Science and Technology
Awarded by Future Fellowship from the ARC
Inductively coupled plasma optical emission spectrometry was performed at the Mark Wainwright Analytical Centre, University of New South Wales by Ms Rabeya Akter. Electron microscopy was performed at the Bio21 Advanced Microscopy Facility, The University of Melbourne by Dr Nghia Truong and Mr Song Yang Khor. J. L. would like to thank Dr Lars Esser for their guidance for designing and analysing the MRI experiments. This work was carried out within the Australian Research Council (ARC) Centre of Excellence in Convergent Bio-Nano Science and Technology (Project No. CE140100036). J. L. acknowledges the financial support from the Australian Government Research Training Program Scholarship. B. A. M is supported by a National Imaging Facility (NIF) Fellowship and the 7 T MRI is part of The University of Melbourne node of NIF funded through the Australian Government NCRIS program. J. F. Q. acknowledges receipt of a Future Fellowship from the ARC (FT170100144). T. P. D. is grateful for the award of an Australian Laureate Fellowship from the ARC.