Expression of adhesion molecules on granulocytes and monocytes following myocardial infarction in rats drinking white wine.
Nikolina Režić-Mužinić, Angela Mastelić, Benjamin Benzon, Anita Markotić, Ivana Mudnić, Ivica Grković, Mia Grga, Ana Marija Milat, Nikola Ključević, Mladen Boban
PLoS One | Published : 2018
Neutrophils and monocytes through their CD15s, CD11b and CD44 adhesion molecules are implicated in the initiation and resolution of cardiac inflammation as well as in healing processes after the myocardial infarction (MI). The aim of this study was to determine the effect of white wine consumption on granulocyte and monocyte CD15s, CD11b, and CD44 expression 24h after the surgically inflicted MI. Granulocytes and monocytes were analyzed by flow cytometry, using whole blood of male Sprague-Dawley rats that consumed white wine for 4 weeks. This group was compared with water only drinking controls, sham animals (subject to surgery without myocardial infarction) and baseline group (intact animal..View full abstract