Journal article
Longitudinal changes in retinotopic rod function in intermediate age-related macular degeneration
CT Nguyen, RG Fraser, R Tan, E Caruso, JJ Lek, RH Guymer, CD Luu
Investigative Ophthalmology and Visual Science | ASSOC RESEARCH VISION OPHTHALMOLOGY INC | Published : 2018
Open access
Abstract
PURPOSE. Although impairment of rod function in the early stages of age-related macular degeneration (AMD) has been well recognized, data on longitudinal changes in rod function at multiple retinal locations remain limited. This study investigated the longitudinal changes in retinotopic rod function in eyes with intermediate AMD (iAMD). METHODS. Complete ophthalmic examination, multimodal imaging, and scotopic perimetry were performed at baseline and at 12-month follow-up. Perimetric scotopic retinal sensitivities for the 505-nm stimulus were repeatedly measured for 20 minutes after exposing to a single photobleach (~30%). The rod intercept time (RIT) and retinal sensitivity at seven retinal..
View full abstractGrants
Awarded by Macular Disease Foundation Australia
Funding Acknowledgements
Supported by a Macular Disease Foundation Australia grant (CDL), a National Health and Medical Research Council Practitioner Fellowship (#1103013, RHG), and Ophthalmic Research Institute of Australia (JJL). The Centre for Eye Research Australia (CERA) receives Operational Infrastructure Support from the Victorian Government.