Drug treatments for alzheimer's disease

Abstract

Alzheimer's disease (AD), the commonest cause of dementia, presents many challenges in pharmacological management. Newer cholinergic agents are modestly effective in improving or delaying decline in cognitive function, and should be considered for all with mild to moderate AD unless contra-indicated. Other cognitive agents with possible, but more modest, efficacy include Vitamin E, seleghe and ginkgo biloba. Potential new therapies, including anti-inflammatory agents, monoamine oxidase type B inhibitors and oestrogen are undergoing trials in Australia and New Zealand and may be available soon. Behavioural and psychological symptoms of dementia should be managed first by non-pharmacological a..