Evaluation of Osteogenic Potentials of Avian Demineralized Bone Matrix in the Healing of Osseous Defects in Pigeons
Reza Sanaei, Jalila Abu, Mojgan Nazari, Mohd AB Zuki, Zeenathul N Allaudin
Veterinary Surgery | WILEY-BLACKWELL | Published : 2015
OBJECTIVES: To evaluate avian allogeneic demineralized bone matrix (DBM) in the healing of long bone defects as a function of geometry and time in a pigeon model. STUDY DESIGN: Experimental. ANIMALS: Adult rock pigeons (n = 60). METHODS: Midshaft ulnar osseous defects were grafted with 2 geometric forms of DBM (tubular vs. chipped) and stabilized with a hybrid fixator. Autologous chips of sternal keel were used in a third group as control. Outcomes were evaluated by radiography and histology/histomorphometry at 4, 8, 12, and 24 weeks postoperatively. RESULTS: Despite an early rapid healing response, autografts plateaued (histologic score and new bone area) by 8 weeks with no significant impr..View full abstract
Awarded by Research University Grant Scheme (RUGS), Universiti Putra Malaysia
This work was supported by Research University Grant Scheme (RUGS) No. 04-03-08-0459RU, Universiti Putra Malaysia.