Journal article

Economic evaluation of a dietary intervention for adults with major depression (the "SMILES" trial)

Mary Lou Chatterton, Cathrine Mihalopoulos, Adrienne O'Neil, Catherine Itsiopoulos, Rachelle Opie, David Castle, Sarah Dash, Laima Brazionis, Michael Berk, Felice Jacka

BMC PUBLIC HEALTH | BMC | Published : 2018


BACKGROUND: Recently, the efficacy of dietary improvement as a therapeutic intervention for moderate to severe depression was evaluated in a randomised controlled trial. The SMILES trial demonstrated a significant improvement in Montgomery-Åsberg Depression Rating Scale scores favouring the dietary support group compared with a control group over 12 weeks. We used data collected within the trial to evaluate the cost-effectiveness of this novel intervention. METHODS: In this prospective economic evaluation, sixty-seven adults meeting DSM-IV criteria for a major depressive episode and reporting poor dietary quality were randomised to either seven sessions with a dietitian for dietary support o..

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Awarded by National Health and Medical Research Council (NHMRC)

Funding Acknowledgements

This project was funded by the National Health and Medical Research Council (NHMRC grant number APP1021347). Woolworths Limited provided sponsorship in the form of food vouchers for participants. Village cinemas donated cinema vouchers and Carman's Fine Foods donated muesli bars for participants. A grant from Meat and Livestock Australia (2013) funded biochemistry data collected and analysed as part of the SMILES trial. These sponsors had no role in the design, analysis or preparation of the manuscript for publication.