Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility
Nguyen Quynh-Nhu, Nadeen Zerafa, Seng H Liew, F Hamish Morgan, Andreas Strasser, Clare L Scott, Jock K Findlay, Martha Hickey, Karla J Hutt
Cell Death & Disease | NATURE PUBLISHING GROUP | Published : 2018
Awarded by National Health and Medical Research Council Australia
Awarded by Leukemia and Lymphoma Society Specialized Center of Research Program Grant
Awarded by Cancer Council Victoria
Awarded by National Breast Cancer Foundation
This work was supported by fellowships and grants from the National Health and Medical Research Council Australia (Project Grant #1007027, Program Grant #1016701, and Fellowships KJH (#1050130), AS (#1020363)); the Leukemia and Lymphoma Society Specialized Center of Research Program Grant (#7001-13); and the Cancer Council Victoria Grant in Aid (#1052309); National Breast Cancer Foundation (#NC14-001). This work was made possible through Victorian State Government Operational Infrastructure Support and Australian Government NHMRC IRIISS. The authors acknowledge the facilities, scientific, and technical assistance of Monash Micro Imaging, the Monash Animal Research Platform, and the Monash Histology Platform, Monash University, Victoria, Australia. The authors thank Dr Dagmar Wilhelm, The University of Melbourne, for supplying the rabbit anti-FOXL2 antibody used in this study.