Predictors of new-onset chronic kidney disease in patients managed surgically for T1a renal cell carcinoma: An Australian population-based analysis

Abstract

Background: New-onset chronic kidney disease (CKD) following surgical management of kidney tumors is common. This study evaluated risk factors for new-onset CKD after nephrectomy for T1a renal cell carcinoma (RCC) in an Australian population-based cohort. Methods: There were 551 RCC patients from the Australian states of Queensland and Victoria included in this study. The primary outcome was new-onset CKD (eGFR <60 mL/min per 1.73 m2) and the secondary outcome was new-onset moderate-severe CKD (<45 mL/min per 1.73 m2). Multivariable logistic regression was used to evaluate associations between patient, tumor and health-service characteristics and these outcomes. Results: Forty percent (219/5..