Journal article

Exploring the space of gene/species reconciliations with transfers

YB Chan, V Ranwez, C Scornavacca

Journal of Mathematical Biology | SPRINGER HEIDELBERG | Published : 2015

Abstract

Reconciliations between gene and species trees have important applications in the study of genome evolution (e.g. sequence orthology prediction or quantification of transfer events). While numerous methods have been proposed to infer them, little has been done to study the underlying reconciliation space. In this paper, we characterise the reconciliation space for two evolutionary models: the (Formula presented.) (duplication, loss and transfer) model and a variant of it—the no-(Formula presented.) model—which does not allow (Formula presented.) events (a transfer immediately followed by a loss). We provide formulae to compute the size of the corresponding spaces and define a set of transfor..

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Funding Acknowledgements

This work was partially funded by the French Agence Nationale de la Recherche Investissements d'avenir/Bioinformatique (ANR-10-BINF-01-02, Ancestrome). This publication is contribution no. 2014-220 of the Institut des Sciences de l'Evolution de Montpellier (ISEM, UMR 5554)