Journal article
1 Versus 2-cm Excision Margins for pT2-pT4 Primary Cutaneous Melanoma (MelMarT): A Feasibility Study
MD Moncrieff, D Gyorki, R Saw, AJ Spillane, H Peach, D Oudit, J Geh, P Dziewulski, E Wilson, P Matteucci, R Pritchard-Jones, R Olofsson Bagge, FC Wright, N Crampton, O Cassell, N Jallali, A Berger, J Kelly, S Hamilton, A Durrani Show all
Annals of Surgical Oncology | SPRINGER | Published : 2018
Open access
Abstract
Background: There is a lack of consensus regarding optimal surgical excision margins for primary cutaneous melanoma > 1 mm in Breslow thickness (BT). A narrower surgical margin is expected to be associated with lower morbidity, improved quality of life (QoL), and reduced cost. We report the results of a pilot international study (MelMarT) comparing a 1 versus 2-cm surgical margin for patients with primary melanoma > 1 mm in BT. Methods: This phase III, multicentre trial [NCT02385214] administered by the Australia & New Zealand Medical Trials Group (ANZMTG 03.12) randomised patients with a primary cutaneous melanoma > 1 mm in BT to a 1 versus 2-cm wide excision margin to be performed with sen..
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Awarded by Cancer Council NSW
Funding Acknowledgements
Study funded by a Grant from the Cancer Council NSW [Grant Ref: 14-15]. The trial committee would like to acknowledge Alex Economides, Project Officer for MelMarT at ANZMTG