Journal article

A peer-support lifestyle intervention for preventing type 2 diabetes in India: A cluster-randomized controlled trial of the Kerala Diabetes Prevention Program

Kavumpurathu R Thankappan, Thirunavukkarasu Sathish, Robyn J Tapp, Jonathan E Shaw, Mojtaba Lotfaliany, Rory Wolfe, Pilvikki Absetz, Elezebeth Mathews, Zahra Aziz, Emily D Williams, Edwin B Fisher, Paul Z Zimmet, Ajay Mahal, Sajitha Balachandran, Fabrizio D'Esposito, Priyanka Sajeev, Emma Thomas, Brian Oldenburg

PLOS MEDICINE | PUBLIC LIBRARY SCIENCE | Published : 2018

Abstract

BACKGROUND: The major efficacy trials on diabetes prevention have used resource-intensive approaches to identify high-risk individuals and deliver lifestyle interventions. Such strategies are not feasible for wider implementation in low- and middle-income countries (LMICs). We aimed to evaluate the effectiveness of a peer-support lifestyle intervention in preventing type 2 diabetes among high-risk individuals identified on the basis of a simple diabetes risk score. METHODS AND FINDINGS: The Kerala Diabetes Prevention Program was a cluster-randomized controlled trial conducted in 60 polling areas (clusters) of Neyyattinkara taluk (subdistrict) in Trivandrum district, Kerala state, India. Part..

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Grants

Awarded by National Health and Medical Research Council


Awarded by Fogarty International Centre


Awarded by NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES


Funding Acknowledgements

The research was supported by funding from the National Health and Medical Research Council (1005324), https://www.nhmrc.gov.au/, and the Fogarty International Centre (D43TW008332), https://www.fic.nih.gov/. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.