Dynamic action potential clamp predicts functional separation in mild familial and severe de novo forms of SCN2A epilepsy
Geza Berecki, Katherine B Howell, Yadeesha H Deerasooriya, Maria Roberta Cilio, Megan K Oliva, David Kaplan, Ingrid E Scheffer, Samuel F Berkovic, Steven Petrou
Proceedings of the National Academy of Sciences | NATL ACAD SCIENCES | Published : 2018
Related Projects (1)
Awarded by Australian Research Council Centre of Excellence for Integrative Brain Function Grant
Awarded by National Health and Medical Research Council (NHMRC) programme
Awarded by NHMRC Fellowship
We thank the patients and their families for participating in our research; and Ian C. Forster for helpful comments on an earlier version of this manuscript. This study was supported by Australian Research Council Centre of Excellence for Integrative Brain Function Grant CE14010007; National Health and Medical Research Council (NHMRC) programme Grant 10915693 and NHMRC Fellowship GNT1005050 (to S. P.); and a Practitioner fellowship (to I. E. S.). K. B. H. was supported by a clinician-scientist fellowship from the Murdoch Childrens Research Institute. G. B. was funded by RogCon, Inc. The Florey Institute of Neuroscience and Mental Health is supported by Victorian State Government infrastructure funds.