Journal article

MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors

Anuratha Sakthianandeswaren, Marie J Parsons, Dmitri Mouradov, Ruth N MacKinnon, Bruno Catimel, Sheng Liu, Michelle Palmieri, Christopher Love, Robert N Jorissen, Shan Li, Lachlan Whitehead, Tracy L Putoczki, Adele Preaudet, Cary Tsui, Cameron J Nowell, Robyn L Ward, Nicholas J Hawkins, Jayesh Desai, Peter Gibbs, Matthias Ernst Show all

Cancer Discovery | AMER ASSOC CANCER RESEARCH | Published : 2018


Awarded by NHMRC

Awarded by Cancer Council Victoria

Awarded by NHMRC Senior Research Fellowship

Awarded by National Breast Cancer Foundation

Funding Acknowledgements

The authors thank the Victorian Cancer Biobank and BioGrid Australia for provision of patient specimens and data, and Prof. M. Schwab at the DKFZ for access to colorectal cancer cell lines. This work was supported by an NHMRC Project Grant (APP1079364 to O.M. Sieber, M. Buchert, J. Desai, and I. Street), a Cancer Council Victoria Grant-in-Aid (APP1060964 to O.M. Sieber and R.L. Ward), the Ludwig Institute for Cancer Research (O.M. Sieber), the Cancer Therapeutics Cooperative Research Centre (I. Street), an NHMRC Senior Research Fellowship (APP1136119 to O.M. Sieber), a Cancer Therapeutics CRC Top Up PhD Scholarship (M. J. Parsons), and the Victorian Government's Operational Infrastructure Support Program (O.M. Sieber).