Journal article

Association between birth weight and educational attainment: an individual-based pooled analysis of nine twin cohorts

Aline Jelenkovic, Janne Mikkonen, Pekka Martikainen, Antti Latvala, Yoshie Yokoyama, Reijo Sund, Eero Vuoksimaa, Esther Rebato, Joohon Sung, Jina Kim, Jooyeon Lee, Sooji Lee, Maria A Stazi, Corrado Fagnani, Sonia Brescianini, Catherine A Derom, Robert F Vlietinck, Ruth JF Loos, Robert F Krueger, Matt Mcgue Show all

Journal of Epidemiology & Community Health | BMJ PUBLISHING GROUP | Published : 2018

Abstract

BACKGROUND: There is evidence that birth weight is positively associated with education, but it remains unclear whether this association is explained by familial environmental factors, genetic factors or the intrauterine environment. We analysed the association between birth weight and educational years within twin pairs, which controls for genetic factors and the environment shared between co-twins. METHODS: The data were derived from nine twin cohorts in eight countries including 6116 complete twin pairs. The association between birth weight and educational attainment was analysed both between individuals and within pairs using linear regression analyses. RESULTS: In between-individual ana..

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Grants

Awarded by Academy of Finland


Awarded by Centre of Research Excellence from the National Health and Medical Research Council


Awarded by National Institute on Aging


Awarded by ENGAGE - European Network for Genetic and Genomic Epidemiology, FP7-HEALTH-F4-2007


Awarded by National Institute of Alcohol Abuse and Alcoholism


Awarded by Academy of Finland Center of Excellence in Complex Disease Genetics


Awarded by Global Research Network Program of the National Research Foundation


Funding Acknowledgements

This work was supported by the Academy of Finland (grant #266592). The Australian Twin Registry is supported by a Centre of Research Excellence (grant ID 1079102) from the National Health and Medical Research Council administered by the University of Melbourne. The Carolina African American Twin Study of Aging (CAATSA) was funded by a grant from the National Institute on Aging (grant 1RO1-AG13662-01A2) to KEW. Since its origin the East Flanders Prospective Survey has been partly supported by grants from the Fund of Scientific Research, Flanders and Twins, a non-profit Association for Scientific Research in Multiple Births (Belgium). Data collection and analyses in Finnish twin cohorts have been supported by ENGAGE - European Network for Genetic and Genomic Epidemiology, FP7-HEALTH-F4-2007, grant agreement number 201413, National Institute of Alcohol Abuse and Alcoholism (grants AA-12502, AA-00145, and AA-09203 to R J Rose, the Academy of Finland Center of Excellence in Complex Disease Genetics (grant numbers: 213506, 129680), and the Academy of Finland (grants 100499, 205585, 118555, 141054, 265240, 263278 and 264146 to J Kaprio). Anthropometric measurements of the Hungarian twins were supported by Medexpert Ltd., Budapest, Hungary. Korean Twin-Family Register was supported by the Global Research Network Program of the National Research Foundation (NRF 2011-220-E00006).