Aerobic and strength training exercise programme for cognitive impairment in people with mild to moderate dementia: the DAPA RCT
Sarah E Lamb, Dipesh Mistry, Sharisse Alleyne, Nicky Atherton, Deborah Brown, Bethan Copsey, Sukhdeep Dosanjh, Susanne Finnegan, Beth Fordham, Frances Griffiths, Susie Hennings, Iftekhar Khan, Kamran Khan, Ranjit Lall, Samantha Lyle, Vivien Nichols, Stavros Petrou, Peter Zeh, Bart Sheehan
HEALTH TECHNOLOGY ASSESSMENT | NIHR JOURNALS LIBRARY | Published : 2018
BACKGROUND: Approximately 670,000 people in the UK have dementia. Previous literature suggests that physical exercise could slow dementia symptom progression. OBJECTIVES: To estimate the clinical effectiveness and cost-effectiveness of a bespoke exercise programme, in addition to usual care, on the cognitive impairment (primary outcome), function and health-related quality of life (HRQoL) of people with mild to moderate dementia (MMD) and carer burden and HRQoL. DESIGN: Intervention development, systematic review, multicentred, randomised controlled trial (RCT) with a parallel economic evaluation and qualitative study. SETTING: 15 English regions. PARTICIPANTS: People with MMD living in the ..View full abstract
Awarded by MRC
This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full programme and will be published in full in Health Technology Assessment Vol. 22, No. 28. See the NIHR Journals Library website for further project information. Additional funding was provided by the Oxford NIHR Biomedical Research Centre and the Oxford NIHR Collaboration for Leadership in Applied Health Research and Care.