Behavioral Outcomes of Infant Colic in Toddlerhood: A Longitudinal Study

Abstract

Objective: To assess whether infants with colic that resolved before 6 months of age have poorer medium-term outcomes than infants without colic. Study design: Comparative study of 2 prospective, community-based cohorts of children aged 2-3 years in Melbourne, Australia: children from the Baby Biotics study, with previously diagnosed Wessel criteria of colic without problem crying at 6 months (True Colic Cohort), vs children from the Baby Business trial, without problem crying at 1, 4, and 6 months (No Colic Cohort). Caregiver report of child internalizing and externalizing behaviors (primary outcome), temperament, regulatory (crying/sleeping/feeding) problems, and family functioning at chil..