Age-Related Decline in Primary CD8( ) T Cell Responses Is Associated with the Development of Senescence in Virtual Memory CD8( ) T Cells
Kylie M Quinn, Annette Fox, Kim L Harland, Brendan E Russ, Jasmine Li, Thi HO Nguyen, Liyen Loh, Moshe Olshanksy, Haroon Naeem, Kirill Tsyganov, Florian Wiede, Rosela Webster, Chantelle Blyth, Xavier YX Sng, Tony Tiganis, David Powell, Peter C Doherty, Stephen J Turner, Katherine Kedzierska, Nicole L La Gruta
Cell Reports | CELL PRESS | Published : 2018
Awarded by National Health and Medical Research Council (NHMRC)
Awarded by NHMRC
We thank Anthony W. Purcell for critical reading of the manuscript, staff at the University of Melbourne and Monash University flow cytometry facilities for excellent technical assistance with cell sorting (Catherine Li, Tina Luke, Angela Hind, Lankesha Yapa, Vanta Jameson, Joshua Kie, Andrew Fryga, Kathryn Flanagan, Michael Reitsma, and Adam Dinsdale), and staff at the University of Melbourne and Monash University animal facilities for excellent animal husbandry of the aged mouse colony, particularly Emily Humphris, Caron Maxim, and Katrina Parr. This work was supported by a Rebecca L. Cooper Medical Research Foundation Grant (to K.M.Q.), a Sylvia and Charles Viertel Senior Medical Research Fellowship (to N.L.L.G.), a National Health and Medical Research Council (NHMRC) Senior Research Fellowship AI1102792 (to K.K.), an NHMRC Program Grant AI1071916 (to N.L.L.G., K.K., S.J.T., and P.C.D.), a Project Grant AI1046333 (to N.L.L.G.), and internal funding from University of Melbourne and Monash University.