Journal article

Ten-Year Outcomes of First-Episode Psychoses in the MRC ÆSOP-10 Study.

Camice J Revier, Ulrich Reininghaus, Rina Dutta, Paul Fearon, Robin M Murray, Gillian A Doody, Tim Croudace, Paola Dazzan, Margaret Heslin, Adanna Onyejiaka, Eugenia Kravariti, Julia Lappin, Ben Lomas, James B Kirkbride, Kim Donoghue, Craig Morgan, Peter B Jones

Journal of Nervous and Mental Disease | Published : 2015


It has long been held that schizophrenia and other psychotic disorders have a predominately poor course and outcome. We have synthesized information on mortality, clinical and social outcomes from the ÆSOP-10 multicenter study, a 10-year follow-up of a large epidemiologically characterized cohort of 557 people with first-episode psychosis. Symptomatic remission and recovery were more common than previously believed. Distinguishing between symptom and social recovery is important given the disparity between these; even when symptomatic recovery occurs social inclusion may remain elusive. Multiple factors were associated with an increased risk of mortality, but unnatural death was reduced by 9..

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University of Melbourne Researchers