Ten-Year Outcomes of First-Episode Psychoses in the MRC ÆSOP-10 Study.
Camice J Revier, Ulrich Reininghaus, Rina Dutta, Paul Fearon, Robin M Murray, Gillian A Doody, Tim Croudace, Paola Dazzan, Margaret Heslin, Adanna Onyejiaka, Eugenia Kravariti, Julia Lappin, Ben Lomas, James B Kirkbride, Kim Donoghue, Craig Morgan, Peter B Jones
Journal of Nervous and Mental Disease | Published : 2015
It has long been held that schizophrenia and other psychotic disorders have a predominately poor course and outcome. We have synthesized information on mortality, clinical and social outcomes from the ÆSOP-10 multicenter study, a 10-year follow-up of a large epidemiologically characterized cohort of 557 people with first-episode psychosis. Symptomatic remission and recovery were more common than previously believed. Distinguishing between symptom and social recovery is important given the disparity between these; even when symptomatic recovery occurs social inclusion may remain elusive. Multiple factors were associated with an increased risk of mortality, but unnatural death was reduced by 9..View full abstract
Awarded by Medical Research Council
Awarded by Wellcome Trust