Ectodermal markers of early developmental impairment in very preterm individuals.
Nadia Vilahur, Matthew PG Allin, Muriel Walshe, Chiara Nosarti, Larry Rifkin, Robin M Murray, Araceli Rosa
Psychiatry Res | Published : 2012
Individuals born very preterm (before 33 weeks' gestation; VPT) are at risk of life-long, neurological impairments, behavioural and other health problems. It is not clear whether these neurodevelomental abnormalities originate prenatally, postnatally or a combination of both. Dermatoglyphics are stable ectodermal markers of neurodevelopmental disruption in the early prenatal period, as it has previously been reported in neuropsychiatric disorders such as schizophrenia or bipolar disorder. We have analyzed the dermatoglyphic variable total a-b ridge count (TABRC), which is a sensitive marker of ectodermal disruption during the first 24 weeks of foetal development, in 142 very preterm (VPT) in..View full abstract