Factor structures of the neurocognitive assessments and familial analysis in first-episode schizophrenia patients, their relatives and controls.
Qiang Wang, Evangelos Vassos, Wei Deng, Xiaohong Ma, Xun Hu, Robin M Murray, David A Collier, Tao Li
Australian & New Zealand Journal of Psychiatry | Published : 2010
OBJECTIVES: Schizophrenia patients have a wide range of cognitive deficits. To explore the structure of these deficits and index their psychometric properties in order to define the major separable factors, exploratory factor analysis (EFA) was performed on a series of neuropsychological test results in a sample of Han Chinese first-episode schizophrenia patients, their relatives and controls without mental illness. METHODS: The factors derived from the composite sample were tested with confirmatory factor analysis (CFA) in each of the subsamples. The heritability of each factor was estimated by using the mixed linear model in order to determine whether the common factor scores describe the ..View full abstract