Journal article

EFFECTS OF ACUTE ADMINISTRATION OF 2-HYDROXYLATED METABOLITES OF ESTROGENS ON LH AND PROLACTIN SECRETION IN MALE AND FEMALE PREPUBERTAL RATS

AK BRAR, G FINK

JOURNAL OF ENDOCRINOLOGY | J ENDOCRINOLOGY LTD | Published : 1984

Abstract

The effects of catechol oestradiol and catechol oestrone on the release of LH and prolactin were investigated in immature male and female Wistar rats. In male rats both catechol oestradiol and catechol oestrone significantly increased the plasma concentration of LH, and catechol oestradiol but not catechol oestrone significantly increased the plasma concentration of prolactin and decreased the pituitary concentration of LH. The parent oestrogens, oestradiol-17 beta and oestrone, had no effect on plasma LH concentrations, but both increased significantly the plasma concentration of prolactin, and oestrone but not oestradiol-17 beta increased the pituitary concentration of LH. In immature fema..

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