Journal article

CHANGES IN LOCAL CEREBRAL GLUCOSE-UTILIZATION ASSOCIATED WITH THE SPONTANEOUS OVULATORY SURGE OF LUTEINIZING-HORMONE IN THE RAT

JK MCQUEEN, G FINK

NEUROENDOCRINOLOGY | KARGER | Published : 1988

Abstract

Brain activity during the spontaneous ovulatory surge of luteinizing hormone (LH) has been studied by measuring local cerebral glucose utilization (LCGU) by the [14C]-2-deoxyglucose method. The LCGU was determined in 37 brain areas and the pituitary gland in conscious, freely moving female rats in the morning and the late afternoon of proestrus. No increases in LCGU were detected, but, unexpectedly, there was a significant decrease in the LCGU measured in the afternoon compared with the morning of proestrus in the medial preoptic and anterior hypothalamic areas, the arcuate nucleus, median eminence and amygdala. Significant reductions in LCGU also occurred in the midbrain central grey and re..

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