Optic nerve tissue displacement during mild intraocular pressure elevation: its relationship to central corneal thickness and corneal hysteresis
Phillip Bedggood, Fumi Tanabe, Allison M McKendrick, Andrew Turpin, Andrew J Anderson, Bang V Bui
OPHTHALMIC AND PHYSIOLOGICAL OPTICS | WILEY | Published : 2018
PURPOSE: To determine the extent to which (1) optic nerve tissue is displaced following mild acute elevation of intraocular pressure, and (2) clinically accessible measures at the anterior eye can be used as a surrogate for such displacements. METHODS: We imaged the optic disc of 21 healthy subjects before and after intraocular pressure (IOP) elevation of ~10 mmHg delivered by ophthalmodynamometry. Steady-state tissue displacement during IOP elevation was assessed axially from OCT data, and laterally from SLO data. Recovery from IOP elevation was assessed by tracking a single vertical B-scan through the cup centre. Anatomical structures were demarcated by three masked clinicians to determine..View full abstract
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Awarded by Australian Research Council
This work was supported by Australian Research Council Future Fellowship FT130100338 and Australian Research Council Linkage Project ARC LP130100055.