Journal article

The role of Chlamydia pneumoniae in acute respiratory tract infections in young children in The Gambia, West Africa.

Martin W Weber, Gowri Gopalakrishna, Agnes Awomoyi, Adam Cunningham, Richard A Adegbola, Adegoke G Falade, Olayinka O Ogunlesi, Hilton C Whittle, E Kim Mulholland

Ann Trop Paediatr | Published : 2006

Abstract

BACKGROUND: Little is known about the role of Chlamydia pneumoniae in the aetiology of acute respiratory tract infections (ARI) in children in developing countries. AIMS: To obtain better information, we studied the presence of C. pneumoniae and its association with clinical signs and symptoms of ARI in children under 5 years of age in The Gambia. METHODS: C. pneumoniae was sought by polymerase chain reaction in nasopharyngeal secretions and/or lung puncture aspirates from 324 infants under 3 months of age and 325 children between 3 months and 5 years of age with malnutrition, with or without pneumonia, and in control children. Clinical signs and symptoms for ARI and the spectrum of other vi..

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