Journal article

The zinc efflux activator SczA protects Streptococcus pneumoniae serotype 2 D39 from intracellular zinc toxicity

Julia E Martin, Katherine A Edmonds, Kevin E Bruce, Gregory C Campanello, Bart A Eijkelkamp, Erin B Brazel, Christopher A McDevitt, Malcolm E Winkler, David P Giedroc

Molecular Microbiology | WILEY | Published : 2017


Awarded by NIH

Awarded by Australian Research Council

Funding Acknowledgements

We thank Dr. John P. Lisher for help with ICP-MS analysis, Dr. Hongwei Wu for help in acquiring NMR spectra, and Adriana Giuliani and Katherine Geiger for help in early cloning of and in vitro mutagenesis experiments with S. pneumoniae SczA. This work was supported by NIH grants GM042569 and GM118157 (to D.P.G.), GM113172 and GM114315 (to M.E.W), and Australian Research Council Discovery Project Grant DP150101856 (to C.A.M). The NMR instrumentation in the METACyt Biomolecular NMR Laboratory at Indiana University was generously supported by a grant from the Lilly Endowment.