Journal article
A novel route to copper(ii) detection using 'click' chemistry-induced aggregation of gold nanoparticles
C Hua, WH Zhang, SRM De Almeida, S Ciampi, D Gloria, G Liu, JB Harper, JJ Gooding
Analyst | ROYAL SOC CHEMISTRY | Published : 2012
DOI: 10.1039/c1an15693d
Abstract
A simple colorimetric method for the detection of copper ions in water is described. This method is based on the 'click' copper(i)-catalyzed azide-alkyne cycloaddition reaction and its use in promoting the aggregation of azide-tagged gold nanoparticles by a dialkyne cross-linker is described. Nanoparticle cross-linking, evidenced as a colour change, is used for the detection of copper ions. The lowest detected concentration by the naked eye was 1.8 μM, with the response linear with log(concentration) between 1.8-200 μM. The selectivity relative to other potentially interfering ions was evaluated.