Journal article

The Walrus and the Carpenter: Complex Regulation of Tumor Immunity in Colorectal Cancer

G Dewson, J Silke

Cell | CELL PRESS | Published : 2018

Abstract

Immune infiltration has been correlated with survival of patients with colorectal cancer. In this issue, Ziegler et al. reveal complex and unexpected connections between loss of STAT3, mitophagy, and the induction of an adaptive immune response that limits the growth of colorectal carcinoma.

University of Melbourne Researchers

Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

G.D. is supported by a grant from Perpetual Impact Funding Harry Secomb Trust (IPAP2017/0788). J.S. is supported by a fellowship from the National Health and Medical Research Council of Australia (1107149). G.D. and J.S. are supported by operational infrastructure grants through the Australian Government IRISS and the Victorian State Government OIS 9000220.