Journal article
Long-term clinical outcomes of transient and persistent no-reflow following percutaneous coronary intervention (PCI): A multicentre Australian registry
S Papapostolou, N Andrianopoulos, SJ Duffy, AL Brennan, AE Ajani, DJ Clark, CM Reid, M Freeman, M Sebastian, L Selkrig, MB Yudi, SQ Noaman, W Chan
Eurointervention | EUROPA EDITION | Published : 2018
Abstract
Aims: The aim of the study was to evaluate long-term outcomes of transient versus persistent no-reflow. Methods and results: A total of 17,547 patients with normal flow post percutaneous coronary intervention (PCI) were compared to 590 patients (3.2%) with transient no-reflow and 144 patients (0.8%) with persistent no-reflow. Long-term all-cause mortality was obtained by linkage with the National Death Index (NDI). No-reflow patients were more likely to have presented with ST-elevation myocardial infarction (STEMI), out-of-hospital cardiac arrest (OHCA) or cardiogenic shock (all p<0.01). Long-term NDI-linked all-cause mortality was highest in patients with persistent no-reflow (31%) followed..
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Awarded by Abbott Laboratories
Funding Acknowledgements
W. Chan is supported by the National Health and Medical Research Council of Australia (NHMRC) Early Career Fellowship (Neil Hamilton Fairley - Clinical Overseas Fellowship; APP1052960). C.M. Reid is supported by an NHMRC Senior Research Fellowship (APP1045862). S.J. Duffy is supported by an NHMRC grant. M.B. Yudi is supported by a combined NHMRC Postgraduate Scholarship (APP 1115163) and a National Heart Foundation Health Professional Scholarship (Award ID 101130). MIG gratefully acknowledges funding from Abbott, AstraZeneca, Medtronic, MSD, Pfizer, Servier and The Medicines Company. These companies did not have access to data or the right to review manuscripts before publication.