Stress Induced Hyperglycemia and the Subsequent Risk of Type 2 Diabetes in Survivors of Critical Illness
Mark P Plummer, Mark E Finnis, Liza K Phillips, Palash Kar, Shailesh Bihari, Vishwanath Biradar, Stewart Moodie, Michael Horowitz, Jonathan E Shaw, Adam M Deane
PLOS ONE | PUBLIC LIBRARY SCIENCE | Published : 2016
OBJECTIVE: Stress induced hyperglycemia occurs in critically ill patients who have normal glucose tolerance following resolution of their acute illness. The objective was to evaluate the association between stress induced hyperglycemia and incident diabetes in survivors of critical illness. DESIGN: Retrospective cohort study. SETTING: All adult patients surviving admission to a public hospital intensive care unit (ICU) in South Australia between 2004 and 2011. PATIENTS: Stress induced hyperglycemia was defined as a blood glucose ≥ 11.1 mmol/L (200 mg/dL) within 24 hours of ICU admission. Prevalent diabetes was identified through ICD-10 coding or prior registration with the Australian Nationa..View full abstract
Salary support was provided to Mark Plummer (National Health and Medical Research Council Postgraduate Scholarship), Liza Phillips (Royal Adelaide Hospital Early Career Fellowship), Palash Kar (Royal Adelaide Hospital A.R. Clarkson Postgraduate Scholarship), Jonathan Shaw (National Health and Medical Research Council of Australia Senior Research Fellow) and Adam Deane (National Health and Medical Research Council of Australia Early Career Fellowship). Data collection was supported by project grants from the Diabetes Australia Research Trust and a University of Adelaide, Discipline of Acute Care Medicine Maurice Sando Project Grant.