Journal article

Mechanisms underlying feed intolerance, in the critically ill: Implications for treatment

Adam Deane, Marianne J Chapman, Robert J Fraser, Laura K Bryant, Carly Burgstad, Nam Q Nguyen

World Journal of Gastroenterology | BAISHIDENG PUBLISHING GROUP INC | Published : 2007


Malnutrition is associated with poor outcomes in critically ill patients. Although nutritional support is yet to be proven to improve mortality in non-malnourished critically ill patients, early enteral feeding is considered best practice. However, enteral feeding is often limited by delayed gastric emptying. The best method to clinically identify delayed gastric emptying and feed intolerance is unclear. Gastric residual volume (GRV) measured at the bedside is widely used as a surrogate marker for gastric emptying, but the value of GRV measurement has recently been disputed. While the mechanisms underlying delayed gastric emptying require further investigation, recent research has given a be..

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