Journal article
The ventricular residence time distribution derived from 4D flow particle tracing: a novel marker of myocardial dysfunction
BT Costello, M Qadri, B Price, S Papapostolou, M Thompson, JL Hare, A La Gerche, M Rudman, AJ Taylor
International Journal of Cardiovascular Imaging | SPRINGER | Published : 2018
Abstract
4D flow cardiac magnetic resonance (CMR) imaging allows visualisation of blood flow in the cardiac chambers and great vessels. Post processing of the flow data allows determination of the residence time distribution (RTD), a novel means of assessing ventricular function, potentially providing additional information beyond ejection fraction. We evaluated the RTD measurement of efficiency of left and right ventricular (LV and RV) blood flow. 16 volunteers and 16 patients with systolic dysfunction (LVEF < 50%) underwent CMR studies including 4D flow. The RTDs were created computationally by seeding virtual ‘particles’ at the inlet plane in customised post-processing software, moving these parti..
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Funding Acknowledgements
The study was funded by a research grant from Monash Institute of Medical Engineering (MIME) and by a National Health and Medical Research Council of Australia grant.