Journal article
Gestational Age and the Cord Blood Lipidomic Profile in Late Preterm and Term Infants
K McCloskey, AM De Livera, F Collier, AL Ponsonby, JB Carlin, P Vuillermin, NA Mellett, K Jayawardana, JM Weir, J Blangero, JE Curran, D Burgner, PJ Meikle
Neonatology | KARGER | Published : 2018
DOI: 10.1159/000487506
Abstract
Background: Lipid metabolism is vital to fetal development and cardiometabolic health and the final weeks of gestation are known to be a time of intense metabolic activity. New techniques such as lipidomics allow investigation of a complex lipidomic profile in infants. Objectives: This research aimed to (1) describe variations in lipidomic profile in late preterm and term infants and (2) compare variations to an adult lipidomic profile with known clinical implications. Methods: The Barwon Infant Study (n = 1,074) is a population-derived pre-birth cohort study. The lipidomic profile of cord blood was measured by liquid chromatography-mass spectrometry in 225 participants and the association b..
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Awarded by Rotary Club of Eureka
Funding Acknowledgements
The initial establishment work and infrastructure for the BIS was supported by the Murdoch Children's Research Institute and Barwon Health. Deakin University is now a partner organization and has provided funding and infrastructure. Funding has been provided by the National Health and Medical Research Council of Australia (607370, 1009044, 102997, 1082037, 1076667, and 1084017), the Jack Brockhoff Foundation, the Scobie Trust, the Shane O'Brien Memorial Asthma Foundation, the Our Women's Our Children's Fundraising Committee Barwon Health, the Rotary Club of Geelong, the Shepherd Foundation, the Ilhan Foundation, and the Operational Infrastructure Support Program of the Victorian Government.