Journal article
REGRESSION OF INTRACEREBRAL LESIONS IN T-PROLYMPHOCYTIC LEUKEMIA TREATED WITH INTRAVENOUS DEOXYCOFORMYCIN
F BRITOBABAPULLE, D HUANG, P LAVENDER, D GALTON, D CATOVSKY
EUROPEAN JOURNAL OF HAEMATOLOGY | MUNKSGAARD INT PUBL LTD | Published : 1988
Abstract
A case of T-prolymphocytic leukaemia (T-PLL) presenting with deafness and confusion is reported. Computerised tomography (CT) of the head showed several well-defined, rounded, high attenuation areas in the temporal, parietal and occipital regions of the brain substance that were suggestive of metastases. Treatment with weekly intravenous deoxycoformycin produced complete resolution of the CT abnormalities together with haematological evidence of disease regression 6 weeks after treatment was started.