Journal article

T cells in coeliac disease: a rational target for diagnosis and therapy

Melinda Y Hardy, Jason A Tye-Din

Nature Reviews Gastroenterology & Hepatology | NATURE PUBLISHING GROUP | Published : 2018

Abstract

New findings show that disease-specific T cells that target gluten in patients with coeliac disease persist for decades. The data highlight a central role for a highly select and stable population of T cells in disease persistence and support the feasibility of diagnostics and therapies targeting these cells.