Journal article
Omega-3 polyunsaturated fatty acids favourably modulate cardiometabolic biomarkers in type 2 diabetes: A meta-analysis and meta-regression of randomized controlled trials
LL O'Mahoney, J Matu, OJ Price, KM Birch, RA Ajjan, D Farrar, R Tapp, DJ West, K Deighton, MD Campbell
Cardiovascular Diabetology | BMC | Published : 2018
Abstract
Background: Randomized controlled trials (RCTs) suggest that supplementation with omega-3 polyunsaturated fatty acids (n-3PUFAs) may favourably modify cardiometabolic biomarkers in type 2 diabetes (T2DM). Previous meta-analyses are limited by insufficient sample sizes and omission of meta-regression techniques, and a large number of RCTs have subsequently been published since the last comprehensive meta-analysis. Updated information regarding the impact of dosage, duration or an interaction between these two factors is therefore warranted. The objective was to comprehensively assess the effect of n-3PUFAs supplementation on cardiometabolic biomarkers including lipid profiles, inflammatory pa..
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Funding Acknowledgements
This study was funded by the Institute for Sport, Physical Activity and Leisure at Leeds Beckett University, and the AGADA Diabetes Education and Research Institute. Neither of the funders were involved in the design, analysis, interpretation, or write-up of this manuscript.