Composite particle formulations of colistin and meropenem with improved in-vitro bacterial killing and aerosolization for inhalation
Sharad Mangal, Heejun Park, Lingfei Zeng, Heidi H Yu, Yu-wei Lin, Tony Velkov, John A Denman, Dmitry Zemlyanov, Jian Li, Qi Tony Zhou
International Journal of Pharmaceutics | ELSEVIER | Published : 2018
Awarded by National Institute of Allergy and Infectious Diseases of the National Institutes of Health
Research reported in this publication was supported by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health under Award Number R01AI132681. Jian Li and Tony Velkov are supported by a research grant from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health (R01AI111965). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Qi (Tony) Zhou is partially supported by the Ralph W. and Grace M. Showalter Research Trust Award. Jian Li is an Australian NHMRC Senior Research Fellow. The authors are grateful for the scientific and technical assistance of the Australian Microscopy & Microanalysis Research Facility at the Future Industries Institute, University of South Australia. The authors are thankful for access to FTIR in Tonglei Li's lab. Kind donations of RS01 DPI device from Plastiape S.p.A. and HPMC capsules from Qualicaps, Inc. are acknowledged.