A pilot study on the seroprevalence of parvovirus B19 infection.
Mary Abraham, Rajeev Rudraraju, Rajesh Kannangai, Koshy George, Thomas Cherian, Dolly Daniel, Sandeep Ramalingam, Gopalan Sridharan
Indian J Med Res | Published : 2002
BACKGROUND & OBJECTIVES: Human parvovirus B 19 (PVB 19) causes aplastic crisis in children with congenital haemolytic anaemia, erythema infectiosum, abortion and stillbirth. Since data on PVB 19 prevalence is lacking in India, a pilot study was undertaken to estimate the prevalence of IgG antibody in children and adults. METHODS: The samples were obtained from children attending our hospital and from volunteer blood donors, majority of whom were from south India. They included 45 children aged 1-5 yr, 39 aged 6-10 yr, 42 aged 11-15 yr and 100 healthy blood donors > 15 yr of age. Sera were tested for the presence of antibody to PVB 19 using a commercial enzyme immuno assay (EIA). RESULTS: Of ..View full abstract