Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy

Mitchell G Lawrence; Daisuke Obinata; Shahneen Sandhu; Luke A Selth; Stephen Q Wong; Laura H Porter; Natalie Lister; David Pook; Carmel J Pezaro; David L Goode; Richard J Rebello; Ashlee K Clark; Melissa Papargiris; Jenna Van Gramberg; Adrienne R Hanson; Patricia Banks; Hong Wang; Birunthi Niranjan; Shivakumar Keerthikumar; Shelley Hedwards; Alisee Huglo; Rendong Yang; Christine Henzler; Yingming Li; Fernando Lopez-Campos; Elena Castro; Roxanne Toivanen; Arun Azad; Damien Bolton; Jeremy Goad; Jeremy Grummet; Laurence Harewood; John Kourambas; Nathan Lawrentschuk; Daniel Moon; Declan G Murphy; Shomik Sengupta; Ross Snow; Heather Thorne; Catherine Mitchell; John Pedersen; David Clouston; Sam Norden; Andrew Ryan; Scott M Dehm; Wayne D Tilley; Richard B Pearson; Ross D Hannan; Mark Frydenberg; Luc Furic; Renea A Taylor; Gail P Risbridger

Journal article

Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy

Mitchell G Lawrence, Daisuke Obinata, Shahneen Sandhu, Luke A Selth, Stephen Q Wong, Laura H Porter, Natalie Lister, David Pook, Carmel J Pezaro, David L Goode, Richard J Rebello, Ashlee K Clark, Melissa Papargiris, Jenna Van Gramberg, Adrienne R Hanson, Patricia Banks, Hong Wang, Birunthi Niranjan, Shivakumar Keerthikumar, Shelley Hedwards Show all

European Urology | ELSEVIER SCIENCE BV | Published : 2018

DOI: 10.1016/j.eururo.2018.06.020

University of Melbourne Researchers

Arun Azad Author The Sir Peter MacCallum Department of Oncology

Richard Pearson Author The Sir Peter MacCallum Department of Oncology

Declan Murphy Author Surgery - St Vincent's Hospital

Luc Furic Author The Sir Peter MacCallum Department of Oncology

Laurence Harewood Author Surgery - Royal Melbourne Hospital

Grants

Awarded by National Health and Medical Research Council of Australia

Awarded by Department of Health and Human Services acting through the Victorian Cancer Agency (CAPTIV Program)

Awarded by U.S. National Institutes of Health

Awarded by CASS Foundation

Awarded by MINIECO

Awarded by Cancer Australia

Awarded by NATIONAL CANCER INSTITUTE

Funding Acknowledgements

This work was supported by funding from the National Health and Medical Research Council of Australia (fellowships to M.G.L. 1035721, G.P.R. 1102752, D.L.G. 1052904, and R.T. 1090204; project grant 1121057 to W.D.T., L.A.S., G.P.R., and R.T.; project grant 1138242 to G.P.R., W.D.T., L.F., S.S., A.A., L.A.S., and M.G.L.), Cancer Australia (project grant 1084546 to L.F., R.D.H., R.B.P, S.S., and G.P.R), the Department of Health and Human Services acting through the Victorian Cancer Agency (Early Career Seed grant to M.G.L. 13033, fellowships to L.F. MCRF16007, R.A.T. MCRF15023, CAPTIV Program), U.S. National Institutes of Health (R01CA174777 to S.M.D.), Prostate Cancer Foundation of Australia fellowship to S.S. (YIA2013), the Prostate Cancer Foundation (Young Investigator Awards to L.A.S., E.C., and R.Y.), Movember-Prostate Cancer Foundation (Challenge Award to S.M.D.), the CASS Foundation (Medical Science grant to M.L. 7139), MINIECO (Juan de la Cierva' fellowship to E.C. IJCI-2014-19129), the Peter MacCallum Cancer Foundation, the EJ Whitten Foundation, the Peter and Lyndy White Foundation, and TissuPath Pathology.