Targeting TrkB with a Brain-Derived Neurotrophic Factor Mimetic Promotes Myelin Repair in the Brain
Jessica L Fletcher, Rhiannon J Wood, Jacqueline Nguyen, Eleanor ML Norman, Christine MK Jun, Alexa R Prawdiuk, Melissa Biemond, Huynh TH Nguyen, Susan E Northfield, Richard A Hughes, David G Gonsalvez, Junhua Xiao, Simon S Murray
The Journal of Neuroscience | SOC NEUROSCIENCE | Published : 2018
Awarded by Australian National Health and Medical Research Council (NHMRC) Project Grants
Awarded by Multiple Sclerosis Research Australia (MSRA) Project Grant
Awarded by MSRA Postdoctoral Fellowship
Awarded by MSRA/NHMRC Early Career Fellowship
This work was supported by Australian National Health and Medical Research Council (NHMRC) Project Grants (APP1058647 to J.X. and APP1105108 to S.S.M.), a Multiple Sclerosis Research Australia (MSRA) Project Grant (13-039; S.S.M. and J.X.), a MSRA Postdoctoral Fellowship (14-056 to J.L.F.), and a MSRA/NHMRC Early Career Fellowship (APP111041 to D.G.G.). We thank Cameron Nowell (Monash University) and Dr. Verena Wimmer (The Florey Institute) for advice on image analysis procedures and automation. Confocal imaging was performed at the Biological Optical Microscope Platform, The University of Melbourne, and the Florey Advanced Microscopy and Immunohistochemistry Service, The Florey Institute of Mental Health and Neuroscience, and Peter MacCallum Centre for Advanced Histology and Microscopy f assistance with EM processing and imaging.