Journal article

Impact of Emergent Circulating Tumor DNA RAS Mutation in Panitumumab-Treated Chemoresistant Metastatic Colorectal Cancer

Tae Won Kim, Marc Peeters, Anne Thomas, Peter Gibbs, Kristina Hool, Jianqi Zhang, Agnes Lee Ang, Bruce Allen Bach, Timothy Price

Clinical Cancer Research | AMER ASSOC CANCER RESEARCH | Published : 2018

DOI: 10.1158/1078-0432.CCR-17-3377

Grants

Funding Acknowledgements

This work was supported by Amgen Inc.

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Keywords

Wild-Type Kras
Fluorouracil
Gene Frequency
Genes, Ras
Clinical Trials, Phase Iii As Topic
Colorectal Neoplasms
Biomarkers, Tumor
Oncology
Cetuximab
Plus
Phase-Iii Trial
Life Sciences & Biomedicine
1st-Line Treatment
Humans
Drug Resistance, Neoplasm
Liquid Biopsy
Dna Mutational Analysis
Multicenter
Bevacizumab
Circulating Tumor Dna
Science & Technology
Leucovorin
Prognosis
Alleles
High-Throughput Nucleotide Sequencing
Open-Label
Antineoplastic Combined Chemotherapy Protocols
Mutation