Journal article

Impact of Emergent Circulating Tumor DNA RAS Mutation in Panitumumab-Treated Chemoresistant Metastatic Colorectal Cancer

Tae Won Kim, Marc Peeters, Anne Thomas, Peter Gibbs, Kristina Hool, Jianqi Zhang, Agnes Lee Ang, Bruce Allen Bach, Timothy Price

Clinical Cancer Research | AMER ASSOC CANCER RESEARCH | Published : 2018

DOI: 10.1158/1078-0432.CCR-17-3377

Grants

Funding Acknowledgements

This work was supported by Amgen Inc.

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Keywords

Colorectal Neoplasms
Multicenter
Science & Technology
Biomarkers, Tumor
Cetuximab
Plus
Clinical Trials, Phase Iii As Topic
Fluorouracil
Life Sciences & Biomedicine
Leucovorin
Open-Label
Wild-Type Kras
Alleles
High-Throughput Nucleotide Sequencing
Antineoplastic Combined Chemotherapy Protocols
Oncology
Phase-Iii Trial
Gene Frequency
Humans
Dna Mutational Analysis
Mutation
1st-Line Treatment
Genes, Ras
Circulating Tumor Dna
Liquid Biopsy
Drug Resistance, Neoplasm
Bevacizumab
Prognosis