Journal article

More evidence is needed. Iron, incident cognitive decline and dementia: a systematic review

Diane E Hosking, Scott Ayton, Nigel Beckett, Andrew Booth, Ruth Peters

THERAPEUTIC ADVANCES IN CHRONIC DISEASE | SAGE PUBLICATIONS LTD | Published : 2018

Abstract

Background: Our aim was to systematically review the relationship between iron and incident cognitive decline or dementia from midlife onwards. Methods: Systematic review of eligible studies using Medline, Embase and PsycINFO® for the period from 1 January 1986 to 2 December 2016 (CRD42016023800), where study populations had a mean age of over 50 years and were free of cognitive impairment or dementia at baseline. Two authors independently extracted data according to eligibility criteria and assessed study characteristics, quality and outcomes. Disagreement was resolved by discussion. Results: A total of 1185 relevant records were identified with 12 full-text articles eligible for review. Si..

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