Journal article
A longitudinal approach to biological psychiatric research: The PsyCourse study
M Budde, H Anderson-Schmidt, K Gade, D Reich-Erkelenz, K Adorjan, JL Kalman, F Senner, S Papiol, TFM Andlauer, AL Comes, EC Schulte, F Klöhn-Saghatolislam, A Gryaznova, M Hake, K Bartholdi, L Flatau, M Reitt, S Quast, S Stegmaier, M Meyers Show all
American Journal of Medical Genetics Part B Neuropsychiatric Genetics | WILEY | Published : 2019
DOI: 10.1002/ajmg.b.32639
Open access
Abstract
In current diagnostic systems, schizophrenia and bipolar disorder are still conceptualized as distinct categorical entities. Recently, both clinical and genomic evidence have challenged this Kraepelinian dichotomy. There are only few longitudinal studies addressing potential overlaps between these conditions. Here, we present design and first results of the PsyCourse study (N = 891 individuals at baseline), an ongoing transdiagnostic study of the affective-to-psychotic continuum that combines longitudinal deep phenotyping and dimensional assessment of psychopathology with an extensive collection of biomaterial. To provide an initial characterization of the PsyCourse study sample, we compare ..
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Awarded by Interdisziplinäres Zentrum für Klinische Forschung, Universitätsklinikum Würzburg
Funding Acknowledgements
German Research Foundation (Deutsche Forschungsgemeinschaft; DFG), Grant/Award Numbers SCHU 1603/4-1, 5-1, 7-1, FA241/16-1; German Federal Ministry of Education and Research (BMBF), Grant/Award Numbers: Integrated Network IntegraMent 01ZX1614K, 01ZX1614G, and 01ZX1614A; German Federal Ministry of Education and Research (BMBF), BipoLife Network; Dr. Lisa Oehler Foundation BONFOR Programme of the University of Bonn; Ilidio Pinho professorship; iBiMED, Grant/Award Number: UID/BIM/04501/2013; German Research Foundation (DFG), Grant/Award Number: FOR2107 DA1151/5-1, SFB-TRR58, Project C09; Interdisciplinary Center for Clinical Research (IZKF) of the medical faculty of Munster, Grant/Award Number: Dan3/012/17