Journal article

Graded Resistance Exercise And Type 2 Diabetes in Older adults (The GREAT2DO study): methods and baseline cohort characteristics of a randomized controlled trial

Kylie A Simpson, Yorgi Mavros, Shelley Kay, Jacinda Meiklejohn, Nathan de Vos, Yi Wang, Qianyu Guo, Renru Zhao, Mike Climstein, Bernard T Baune, Steven Blair, Anthony J O'Sullivan, David Simar, Nalin Singh, Maria A Fiatarone Singh

TRIALS | BMC | Published : 2015


BACKGROUND: Type 2 diabetes (T2D) is projected to affect 439 million people by 2030. Medical management focuses on controlling blood glucose levels pharmacologically in a disease that is closely related to lifestyle factors such as diet and inactivity. Physical activity guidelines include aerobic exercise at intensities or volumes potentially unreachable for older adults limited by many co-morbidities. We aim to show for the first time the efficacy of a novel exercise modality, power training (high-velocity, high-intensity progressive resistance training or PRT), in older adults with T2D as a means for improving glycemic control and targeting many associated metabolic and physiological outco..

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University of Melbourne Researchers


Awarded by National Health and Medical Research Council (NHMRC)

Funding Acknowledgements

We would like to thank our participants for their generous contributions of time and spirit. We would like to thank Harbord Diggers' Freshwater Fitness Center and The STRONG Clinic at Balmain Hospital for the use of their gym facilities and Keiser Sports Health Ltd for donations of resistance training equipment. The Graded Resistance Exercise and Type 2 Diabetes in Older adults (GREAT2DO) study was funded by project grant #512381 from the National Health and Medical Research Council (NHMRC), grants from The Australian Diabetes Society, Diabetes Australia and the Rebecca L. Cooper Foundation. Y. Mavros was supported by the Australian Postgraduate Award Scholarship. Y. Wang was supported by the University of Sydney International Postgraduate Research Scholarship.