Journal article
The relationship between depressive symptoms and restless legs syndrome in two prospective cohort studies
A Szentkiralyi, H Völzke, W Hoffmann, BT Baune, K Berger
Psychosomatic Medicine | LIPPINCOTT WILLIAMS & WILKINS | Published : 2013
Abstract
OBJECTIVE: Cross-sectional studies suggest a strong association between depression and restless legs syndrome (RLS); however, the temporal relationship between the two disorders remains unknown. We tested whether the presence of clinically relevant depressive symptoms (CRDS) is a risk factor for subsequent RLS in the general population. The relationship between prevalent RLS and incident CRDS was also examined. METHODS: Two independent, prospective cohort studies with representative, age-stratified random samples, the Dortmund Health Study (DHS; n = 1312/1122 [baseline/follow-up], median follow-up time = 2.1 years) and the Study of Health in Pomerania (SHIP; n = 4308/3300, median follow-up t..
View full abstractGrants
Awarded by Federal Ministry of Education and Research, Berlin
Funding Acknowledgements
Data collection in the DHS was supported by the German Migraine and Headache Society and by unrestricted grants of equal share from Almirall, Astra-Zeneca, Berlin-Chemie, Boehringer, Boots Health Care, Glaxo-Smith-Kline, Janssen Cilag, McNeil Pharma, MSD Sharp & Dohme, and Pfizer to the University of Muenster. SHIP is part of the Community Medicine Research Net of the University of Greifswald and was funded by Grant ZZ9603 from the Federal Ministry of Education and Research, Berlin, and the Ministers of Cultural and Social Affairs of the Federal State of Mecklenburg-West Pomerania, Schwerin.