Adiposity Estimated Using Dual Energy X-Ray Absorptiometry and Body Mass Index and Its Association with Cognition in Elderly Adults
Evelyn Smith, Phoebe E Bailey, John Crawford, Katherine Samaras, Bernhard T Baune, Lesley Campbell, Nicole Kochan, Jasmine Menant, Daina L Sturnieks, Henry Brodaty, Perminder Sachdev, Julian N Trollor
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY | WILEY | Published : 2014
OBJECTIVES: To determine whether obesity, estimated according to body mass index (BMI), waist circumference, and body fat and abdominal fat assessed using dual-energy X-ray absorptiometry (DEXA), was associated with cognitive performance. DESIGN: Cross-sectional. SETTING: Community based. PARTICIPANTS: Individuals aged 74-94 (N = 406). MEASUREMENTS: BMI, waist circumference, body fat, and abdominal fat were assessed using DEXA. Cognitive performance was assessed using a comprehensive neuropsychological battery. RESULTS: When categorized using BMI, overweight individuals had higher global cognitive function and executive function scores than normal-weight individuals. This relationship did no..View full abstract
Awarded by Dementia Research Grant through the Australian National Health and Medical Research Council
Awarded by Australian National Health and Medical Research Council Program Grant
Awarded by Australian National Health and Medical Research Council Grant
This study was supported by a Dementia Research Grant through the Australian National Health and Medical Research Council (Grant ID 510124). The Sydney MAS is supported by the Australian National Health and Medical Research Council Program Grant (Grant ID 350833). The authors wish to acknowledge the contributions of Brain and Ageing Research Program Staff and all MAS participants was by Genetic Repositories Australia, which is supported by an Australian National Health and Medical Research Council Grant (Grant ID 401184) extracted DNA. Arezoo Assareh and Karen Mather undertook the APOE genotyping in the laboratory of Peter Schofield and John Kwok at Neuroscience Research Australia.