Implicit and explicit procedural learning in patients recently remitted from severe major depression.
Anya Pedersen, Kerstin Küppers, Andreas Behnken, Kristin Kroker, Sonja Schöning, Bernhard T Baune, Fred Rist, Volker Arolt, Thomas Suslow
Psychiatry Res | Published : 2009
In acute depression a high prevalence of deficits in learning and memory performance has been reported. Still, it is unclear whether these cognitive deficits are present after remission of clinical symptoms of depression. The present study compared 20 inpatients recently remitted from severe major depressive disorder (MDD) with 20 healthy matched control participants on two sequence learning tasks: a modified serial reaction-time task (SRT) for implicit learning, which is sensitive to subcortical and frontal impairments, and a serial generation task (SGT) for explicit learning. As compared with performance in healthy controls, implicit and explicit learning were not impaired in recently remi..View full abstract